microfluidic chip virtual model (Autodesk Inc)
Structured Review

Microfluidic Chip Virtual Model, supplied by Autodesk Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/microfluidic chip virtual model/product/Autodesk Inc
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "Nerve growth factor-basic fibroblast growth factor poly-lactide co-glycolid sustained-release microspheres and the small gap sleeve bridging technique to repair peripheral nerve injury"
Article Title: Nerve growth factor-basic fibroblast growth factor poly-lactide co-glycolid sustained-release microspheres and the small gap sleeve bridging technique to repair peripheral nerve injury
Journal: Neural Regeneration Research
doi: 10.4103/1673-5374.344842
Figure Legend Snippet: The schematic diagram of the drug screening biomimetic microfluidic chip. bFGF: Basic fibroblast growth factor; CCU: cell culture unit; CGG: concentration gradient generator; NGF: nerve growth factor.
Techniques Used: Drug discovery, Cell Culture, Concentration Assay
Figure Legend Snippet: Virtual model and schematic of a drug screening biomimetic microfluidic chip. The chip comprises an upstream CGG and downstream parallel CCU, and includes two inlet ports, one liquid outlet, one drug CGG and eight cell culture chambers. CCU: Cell culture unit; CGG: concentration gradient generator.
Techniques Used: Drug discovery, Cell Culture, Concentration Assay
Figure Legend Snippet: Identification of drug concentration gradients of the biomimetic microfluidic chips. (A) Images 1–8 represent eight concentration gradients (more details of concentrations are shown in ). (B) The difference between the theoretical and experimental data of a concentration gradient generator. Data are expressed as mean ± SD. The study was repeated three times.
Techniques Used: Concentration Assay
Figure Legend Snippet: Screening of the drug concentration in primary Schwann cells. (A) Live and dead cell staining of rat Schwann cells under eight different NGF/bFGF drug concentrations on the microfluidic chip. Green is AO stained cells (live), red is PI stained cells (dead). The cell number and proliferation rate of Schwann cells gradually increased from the 1 st chamber to the 4 th chamber, and gradually decreased from the 4 th chamber to the 8 th chamber, reaching a peak in the 4 th chamber (22.86 ng/mL NGF combined with 4.29 ng/mL bFGF). Scale bars: 25 μm. (B) Cell proliferation rate (cell number after culture with NGF/bFGF/initially implanted cell number × 100) under eight different concentrations. (C) Cell number after culture with NGF/bFGF under eight different drug concentrations. Data are expressed as mean ± SD. The above experiments were independently repeated three times. * P < 0.05, vs . other groups (one-way analysis of variance followed by Bonferroni post hoc test). 1–8: Cell culture chambers. AO: Acridine orange solution; bFGF: basic fibroblast growth factor; NGF: nerve growth factor; PI: propidium iodide.
Techniques Used: Concentration Assay, Staining, Cell Culture